MORAN Joseph

Discerning the Roles of CO and Metal Carbonyl Complexes in Primordial Metabolism


The goal of this proposal is to investigate the potential roles of transition metal-bound carbon monoxide as a dehydrating agent, reductant and C1-feedstock in primordial versions of the first five steps of the reductive tricarboxylic acid cycle, a sequence crucial to the early stages of biochemical evolution.